Molnupiravir lowers long COVID risk: study

Antiviral still has a role to play despite guidelines advising against routine use for mild disease, says Associate Professor Paul Griffin.
Associate Professor Paul Griffin
Associate Professor Paul Griffin.

Molnupiravir may cut the risk of long COVID symptoms as well as post-acute death, regardless of a patient’s vaccination status or prior infection, US epidemiologists report. 

Their study of nearly 230,000 veterans with COVID-19 suggests the antiviral is associated with a 14% lower relative risk of post-acute sequalae versus no treatment. 

It was also linked to a 38% and 14% reduced risk of post-acute death and hospital admission, respectively. 

In absolute terms, the risk reduction at 180 days was between 0.9% and 3% across the three main outcomes, the researchers said.