Low-dose opioid–analgesic combo effective in osteoarthritis: review
Researchers say it’s debatable if single-ingredient opioids are appropriate for managing these patients
![Opioid](https://www.ausdoc.com.au/wp-content/uploads/2022/08/opioid-932555698-9.jpg)
A combination of low-dose opioids and simple analgesics may be preferable for osteoarthritis compared with single-ingredient opioids, an Australian study finds.
Not only is pain relief improved but patients are less likely to experience adverse events, researchers say after conducting a systematic review and meta-analysis of 36 randomised, placebo-controlled trials.