Major Aussie study finds statins cut major CV events by 30% in healthy over-70s
Statins reduce cardiovascular events in patients over 70 without increasing serious adverse events, an Australian randomised controlled trial has found — the first to demonstrate the benefit in this age group.
The medication did not lead to an increase in disability-free survival, but researchers said the findings would likely still lead to updated guidelines.
Of 9971 patients — all aged over 70, living independently and with no history of cardiovascular disease, diabetes or dementia — 4984 received atorvastatin and 4987 received placebo.
In the STAREE (STAtins for Reducing Events in the Elderly) randomised controlled trial, mean age was 74.5, and 51.9% were women. Follow-up was a median of 5.9 years.