Metformin has ‘clear metabolic benefits’ in PCOS, review finds

The diabetes drug was found to be superior for weight loss and improving lipids than placebo.
Rachel Fieldhouse

Metformin has clear benefits for women with PCOS and should be considered for those with overweight or obesity to improve weight loss, insulin resistance and lipids, say doctors.

Their systematic review — which informed the updated guidelines released last month — provides strong evidence that the diabetes drug is superior to placebo for PCOS management, with or without lifestyle changes.