Methotrexate shows promise for inflammatory hand OA in Aussie study
The drug could be effective for patients with an inflammatory phenotype, Dr Paul Kubler says.
Methotrexate is a safe and effective low-cost treatment for adults with symptomatic hand osteoarthritis and synovitis, Australian rheumatologists report in a landmark study.
Their trial is the first to show that the immunosuppressant provides a moderate but clinically meaningful benefit for reducing hand osteoarthritis (OA)-related pain and stiffness compared with placebo.
