Miscarriage risk from OTC thrush meds could 'prompt rethink'

Higher doses increase risk of cardiac anomalies by 80%: study

A common over-the-counter thrush medication more than doubles a woman’s risk of miscarriage if taken in early pregnancy, a study shows.

pregnant woman in pharmacy

Oral fluconazole, used to treat vaginal yeast infections, was linked to a twofold risk of miscarriage at low dose, and three times the risk at high dose, the Canadian study shows.

In addition, a dose higher than 150mg increased the risk of cardiac septal closure anomalies by 80%, the study found.

The researchers carried out a nested case-control study,