More questions than answers with esketamine, expert says

The trial that led to esketamine's FDA registration has just been published

A leading US psychiatrist has urged caution on the use of intranasal esketamine, which was recently approved as a treatment for refractory depression by the country’s Food and Drug Administration.

nasal spray

Professor Alan Schatzberg, a former president of the American Psychiatric Association, lists “worrisome findings” and calls for a “concise framework for assessing the risk-benefit balance for using this formulation of ketamine”, in an editorial in the American Journal of Psychiatry.

The article by the Stanford University professor accompanies the

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