NOACs 'better for kidneys': long-term data

The first meta-analysis appraising long-term renal outcomes show NOACs are superior to warfarin for patients with non-valvular AF

Patients prescribed non-vitamin K antagonist oral anticoagulants (NOACs) for non-valvular AF have significantly better renal outcomes than those on warfarin, according to the largest meta-analysis to date.

Although NOACs have been shown to have a more favourable bleed-risk profile, previous meta-analyses on renal benefit have had contradictory results, the researchers say.

Their large systematic review and meta-analysis confirms that using NOACs in non-valvular AF yields better short- and long-term renal results, including reduced risks of both acute kidney injury and end-stage