Off-label quetiapine ‘ups risk of major CV events’

Danish researchers say off-label use of the antipsychotic should be avoided, particularly in women and over-65s
Dr Cathy Andronis.

Low-dose quetiapine used off label as a sedative carries a higher risk of cardiovascular-related death than Z-drug hypnotics or SSRIs, Danish researchers have found. 

Quetiapine has already been linked to weight gain and elevated LDL cholesterol when used in 400-800mg doses for bipolar disorder or schizophrenia.