One biologic comes out on top in psoriatic arthritis trial

It's the first direct comparison of adalimumab and ixekizumab for the condition

The first head-to-head trial of two biologics for psoriatic arthritis suggests that, while adalimumab and ixekizumab are both effective, ixekizumab may have the edge in patients with active skin disease.

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The SPIRIT H2H clinical trial, funded by Eli Lilly and Company, which makes ixekizumab, compared 24-week results for 269 people randomised to the tumour necrosis factor (TNF) inhibitor, adalimumab, with 262 randomised to the interleukin 17A (IL-17A) antagonist, ixekizumab.

All patients were biologic-naïve and had active