One-off ketamine dose may cut heavy drinking

These are the first results to show the drug interrupts memory forming to curb cravings, authors say

A single injection of ketamine substantially cuts alcohol consumption among heavy drinkers, possibly by interrupting the ‘reward memories’ pathway, researchers say. 

Drinkers given just one dose of IV ketamine at a critical time — straight after looking at pictures of beers and expecting a drink — showed a raft of changes at follow-up 10 days later.

Their weekly  alcohol consumption had fallen by nearly a quarter, they drank on four days, rather than six, in a week, and showed less urge to drink a beer when it was put in front of them.

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