Opportunistic bilateral salpingectomy cuts serous ovarian cancer risk by more than 75%: JAMA study

23% of ovarian carcinomas in patients without fallopian tubes were high-grade serous carcinomas compared with 68% in patients with fallopian tubes.

Opportunistic bilateral salpingectomy reduces the risk of serous ovarian cancer by more than 75% compared with hysterectomy or tubal ligation, research suggests. 

Researchers have compared 40,527 patients who underwent opportunistic bilateral salpingectomy (OBS) with 45,296 patients who had either hysterectomy alone or tubal ligation between 2008 and 2020. 

Five or fewer serous ovarian cancers occurred in the OBS group — the precise number was suppressed for privacy because it was so low — compared with 21 in the other group. 

Ovarian cancer’s five-year survival rate is just 50%.