PBAC approves long-acting injectable PrEP for HIV

Cabotegravir was approved by the TGA last year.

Patients with contraindications to daily oral HIV pre-exposure prophylaxis could soon access a PBS-subsidised long-acting injectable.

Following its September meeting, the PBAC has recommended a streamlined authority listing for long-acting cabotegravir (Apretude) as a HIV pre-exposure prophylaxis (PrEP) alternative.

The antiviral, which was approved by the TGA in 2022, is an integrase strand transfer inhibitor that disrupts the HIV replication cycle.

Patients must have a documented negative HIV test before starting treatment and weigh at least 35kg, according to the product information.