PPIs among the drugs that 'alter' gut microbiome

Seven drug categories 'significantly linked' to changes in intestinal taxa and pathways: study

Common drugs such as proton-pump inhibitors and metformin markedly alter the taxonomic structure and metabolic function as well as antibiotic-resistance genes in the gut microbiome, according to a study from the Netherlands.

Gut

The changes observed could increase the risk of intestinal infections, obesity and other disorders, the authors noted in an abstract presented at the United European Gastroenterology (UEG) Week 2019 in Barcelona, Spain.

Researchers studied relations between 41 commonly used drug categories and gut microbial changes in the general

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