Prednisone can help prevent episodic cluster headache

'This is the study that everyone's been waiting for,' says study author

Prednisone is better than placebo for short-term prevention of episodic cluster headaches and should be used as first-line treatment along with verapamil up-titration, according to a new multicentre randomised controlled trial.

"This is the study that everyone's been waiting for," said Dr Mark Obermann of Asklepios Hospitals Schildautal in Seesen, Germany, the study's first author.

In episodic cluster headache, episodes are interspersed with headache-free intervals lasting months to years, typically following a circadian and circannual pattern

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