Pruritus an itch that patients with CKD can’t seem to scratch

Almost one-quarter of patients with chronic kidney disease not requiring dialysis experience moderate to extreme pruritus, researchers have found.
The characteristics most strongly associated with disruptive itchiness include being older, being female, having advanced kidney disease, or having comorbid diabetes, lung disease or depression.
In a study covering three countries — the US, Brazil and France — researchers surveyed almost 4000 patients with chronic kidney disease stages 3-5 (non-dialysis) asking about uraemic pruritus.
Some 24% experienced moderate to extreme pruritus and more than one in 10 said it was severe to extreme.