Real-world study cautions on kidney damage with popular statin

Data from nearly a million patients link rosuvastatin to a higher risk of kidney damage in a dose-response manner

Rosuvastatin is linked to slightly increased risk of kidney failure compared with atorvastatin, underlining the need to start and stay low with patients who have chronic kidney disease, according to US researchers. 

Their study, of nearly a million patients initiating statin therapy, provides solid real-world data on proteinuria, haematuria and kidney failure with rosuvastatin, finding the risk increases in a dose–response manner.