'Safe' to delay antibiotics in kids with respiratory infections

No difference in symptom severity in children, but fewer side effects: Spanish trial

Children with acute, uncomplicated respiratory infections have similar symptom duration and severity with antibiotics given immediately, delayed or not at all, a randomised trial shows.

Spanish researchers assigned children with acute uncomplicated respiratory infections at 39 GP clinics to receive an immediate antibiotic prescription (148 children), delayed antibiotics (146), or no antibiotic prescription (142).

They found the children's symptom duration and severity was similar in all groups, but gastrointestinal side effects were lower

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