‘Set-and-forget’ cholesterol-busting drug now on the PBS

Associate Professor Ralph Audehm says the drug would be a game changer for high-risk Indigenous patients in particular.
Associate Professor Ralph Audehm
Associate Professor Ralph Audehm.

The potent cholesterol-busting drug inclisiran is now subsidised for adults with hypercholesterolaemia who fail to respond to or tolerate statins and ezetimibe.

Inclisiran (Leqvio) — a small interfering RNA therapy — was added to the PBS on Monday as a third-line alternative to proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in patients with non-familial hypercholesterolaemia and familial heterozygous hypercholesterolaemia.