Offer prostate cancer testing to higher-risk men every two years from age 45: new Aussie guidelines

The first guideline update in a decade has a few changes compared with last year's draft.

Men aged 50-69 should be offered prostate cancer testing every two years, with higher-risk men starting at 45, according to new Australian guidelines approved by the NHMRC.

The first update to the early-detection guidelines in a decade includes several changes from the draft version released in 2025.

The final guidelines do not impose an upper age limit on testing but instead suggest GPs assess patient preferences, comorbidities and whether life expectancy exceeds seven years when deciding whether to continue offering PSA testing every two years to men over 70.

Men over 70 with a PSA level below 5.5µg/L may discontinue testing, while testing should cease when limited life expectancy or comorbidities mean treatment would be unlikely to improve quality or length of life.