Three-year study deems PPIs 'safe'
No link with fractures, pneumonia or CVD, although there is a link to infection
12th June 2019
Taking the proton pump inhibitor pantoprazole for three years does not put patients at increased risk of fractures, pneumonia, CVD, chronic renal disease, cancer or dementia, according to data from the largest clinical trial to date.
However, patients taking the PPI are more susceptible to enteric infections, with a 33% higher risk than people taking placebo, the results show.
The findings from the study of nearly 17,600 people with stable cardiovascular disease and peripheral artery disease should alleviate doctors’ fears over long-term PPIs
