Warning over adverse PPI effect that can lead to seizure: case
A Canadian doctor has shared the case of a patient who developed severe electrolyte imbalance after being continuously prescribed the drugs
A Canadian doctor is reporting a case of severe electrolyte imbalance leading to grand mal epileptic seizure, to draw attention to an under-recognised complication with PPI therapy.
His 55-year-old patient first presented to an outpatient clinic in 2015 with a one-year history of intermittent chronic diarrhoea, up to eight times per day, resulting in a 12kg weight loss.
Her symptoms began shortly after her GP prescribed ranitidine 150mg daily for dyspepsia.
Her ranitidine was changed to omeprazole but her diarrhoea persisted, reported Dr Senyo Tagboto from the Yarmouth Regional Hospital in Nova Scotia.
