Warning over excessive use of common vaginal cream: case

A 50-year-old woman developed life-threatening methaemoglobinaemia after over-applying Vagisil, report US doctors

GPs are being urged to warn patients about the dangers of over-applying OTC medications, after a middle-aged woman developed a potentially life-threatening anaemia after using a common vaginal cream.

The perimenopausal woman, 50, developed methaemoglobinaemia after using Vagisil excessively for her severe, chronic vaginal itch, report doctors from Orlando Regional Healthcare in Florida, US.

The culprit ingredient in the cream is benzocaine, known to produce free radicals that can oxidise haemoglobin into