Watch out for this PPI side effect, doctors urged

Although hyponatraemia-associated with the drugs is rare, it still needs to be recognised in practice, say Dutch researchers

Doctors are being urged to look out for hyponatraemia with proton pump inhibitors after a patient developed the side effect following the use of two different types of the drug.

The Dutch authors say their 67-year-old patient’s experience suggests a class-wide effect, in what they believe is the first such case to be reported.

“Hyponatraemia is worrisome and awareness of medication-induced hyponatraemia, especially due to proton pump inhibitors, is needed,” they write in the BMC Journal of Medical Case