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Sildenafil, tadalafil and vardenafil improve pulmonary arterial hypertension, shows research

Erectile dysfunction drugs sildenafil, tadalafil and vardenafil have significant beneficial effects in pulmonary arterial hypertension, an Australian Cochrane review confirms.


Melbourne researchers investigated the efficacy of phosphodiesterase 5 (PDE5) inhibitors for pulmonary hypertension in adults and children in their systematic review of 36 studies with 2999 participants with pulmonary hypertension from all causes.

Compared with placebo-treated patients, patients with pulmonary arterial hypertension (PAH, also known as Group 1 pulmonary hypertension) treated