How Pfizer and Moderna can update their mRNA vaccines for Omicron in 52 days

  • Opinion
  • Professor Deborah Fuller
  • 6 December 2021

The emergence of the Omicron variant could mean existing vaccines won’t be as effective as they have been.

Deborah Fuller, a microbiologist who has been studying mRNA and DNA vaccines, explains how quickly the current vaccines can be updated.

Coronaviruses use spike proteins to attach to ACE-2 receptors on the surface of human cells and infect them. All mRNA COVID-19 vaccines work by giving instructions in the form of mRNA that direct cells to make a harmless version of the spike protein.

This then induces the human body to produce antibodies.