Adalimumab 'safe and effective' in paediatric ulcerative colitis

​​​​​​​The findings come from the largest trial yet evaluating a biologic therapy in children with the disease, researchers say

Adalimumab provides clinically meaningful rates of remission and response in children with moderate-to-severe ulcerative colitis, clinical trial results show.

girl in fetal position with stomach ache

Overall, 37% of children on the medication had a positive response.

The phase 3 ENVISION I trial is the largest trial yet of a biologic in such children and led to US FDA approval for adalimumab for the indication in February.