Advanced liver fibrosis common in severe psoriasis

The largest study to date shows 79% of those with fibrosis also had a large waist circumference

Patients with severe psoriasis are seven times more likely to have advanced liver fibrosis than the general population, according to British dermatologists.


In the largest study to evaluate the association, researchers found abdominal obesity and insulin resistance were strong predictors.

In the prospective cohort study, 400 patients were recruited from dermatology outpatient visits at one specialist centre serving London and south-east England.

Disease severity was determined by a current or previous psoriasis area severity index