Alteplase of benefit in lacunar stroke, study suggests
![MRI machine](https://www.ausdoc.com.au/wp-content/uploads/2022/08/mri-machne-dreamstime_xxl_29602723-1.jpg)
Patients with lacunar infarcts who reach hospital within 4.5 hours of onset will probably do as well with alteplase as people with other types of ischaemic stroke, a post-hoc trial analysis suggests.
There has been debate about whether lacunar infarcts — subcortical rounded, ovoid or tubular lesions (<20mm diameter) in regions supplied by penetrating arteries — will respond to thrombolysis, because the pathology of these infarcts is unclear.