Anticoagulation halves mortality in severe COVID-19, study shows

A leading cardiologist says an RCT is needed, but he is already anticoagulating hospitalised patients unless contraindicated

Among hospitalised adult COVID-19 patients, prophylactic and therapeutic anticoagulation are associated with much lower rates of intubation and death, a US retrospective study shows.

vial of heparin and syringe

As reported in the Journal of the American College of Cardiology (JACC), doctors examined the association of anticoagulation with mortality, intubation and major bleeding in 4389 people with COVID-19 (median age 65 years, 44% women).

They also conducted subanalyses on the association of therapeutic vs prophylactic anticoagulation