Antifibrotic combo therapy reduces biomarkers in IPF
A subgroup analysis of the INSTAGE trial shows effects on biomarkers depend on the presence or absence of emphysema
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A post-hoc analysis of results from the INSTAGE trial shows that treatment with a combination of nintedanib and sildenafil affects three biomarkers relating to idiopathic pulmonary fibrosis (IPF).
In the INSTAGE trial of people with IPF and a predicted lung diffusion capacity for carbon monoxide (DLCO) of 35% or below, no benefit was found from the combination therapy vs