Antihypertensive deprescribing safe in select patients over 80: trial

Reducing the medication over the short-term is noninferior to usual care, the study finds

Antihypertensive medication can be safely reduced, at least in the short-term, in suitable patients in their 80s, results of a clinical trial show.

senior blood pressure

In the unblinded trial carried out at 69 primary practices in the UK, 569 participants older than 80 with systolic BP below 150mmHg and taking at least two hypertensives were randomised either to deprescription of one antihypertensive or usual care.

All participants were enrolled by GPs who considered the patient could benefit from medication reduction

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