Antipsychotic adverse events highest in over-65s
Large analysis highlights the toxicity of the drugs in older patients and those with dementia
![Adverse events](https://www.ausdoc.com.au/wp-content/uploads/2022/08/pills_adverse_drug_reactions_dreamstime_s_109772747-3.jpg)
Doctors should be aware that antipsychotics are potentially toxic, particularly in older patients and those with dementia, say the authors of a large meta-analysis.
German researchers examined 341 randomised controlled trials comparing second-generation antipsychotics with placebo to determine whether serious adverse events were more common among those on the drugs.