Are anti-TNF 'non-responders' being classified correctly?
Real-world study finds some of the patients appear to have low disease activity
5th July 2019
By Clare Pain
The way physicians are classifying some rheumatoid arthritis patients as ‘non-responders’ to anti-TNFs suggests there is room for improvement in adherence to guidelines, Canadian researchers say.
The researchers examined two registries that included data on 1376 patients prescribed tumour necrosis factor (TNF) inhibitors for RA to better understand the characteristics of those classified as non-responders by doctors.
Depending on the registry, 14% or 18% of patients initiated on an anti-TNF biologic were later classified as non-responders, the researchers