Are anti-TNF 'non-responders' being classified correctly?

Real-world study finds some of the patients appear to have low disease activity

The way physicians are classifying some rheumatoid arthritis patients as ‘non-responders’ to anti-TNFs suggests there is room for improvement in adherence to guidelines, Canadian researchers say.

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The researchers examined two registries that included data on 1376 patients prescribed tumour necrosis factor (TNF) inhibitors for RA to better understand the characteristics of those classified as non-responders by doctors.

Depending on the registry, 14% or 18% of patients initiated on an anti-TNF biologic were later classified as non-responders, the