Assay for CNS infections can pick up cancers too: study

Metagenomic next-generation sequencing can help distinguish the causes of meningoencephalitis, researchers say

A metagenomic next-generation sequencing (mNGS) test of cerebrospinal fluid samples designed to detect CNS infections can also pick up difficult-to-diagnose tumours in the brain and spinal cord, US researchers say.

DNA futuristic image

The test could help distinguish between various autoimmune disorders, infections and malignancies that can all present as meningoencephalitis, the authors say.

Analysis of data from two case-controlled studies with a total of 130

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