Is this autoimmune cause of pruritus being overlooked?
The autoimmune disease nonbullous pemphigoid may be an unrecognised cause of pruritus in the over-65s, a small study suggests.
The study included 125 nursing home residents in the Netherlands with a mean age of 84. Most (75%) of the participants had a history of neurodegenerative disease.
As reported in JAMA Dermatology, pruritus was present in nearly half the participants (47%) and had lasted for more than six weeks in 81% of those with itch.
While three participants had already been diagnosed with bullous pemphigoid, the researchers found four more people with pemphigoid — all of the nonbullous type — yielding an overall prevalence of 6%.