Benign ovarian cysts 'common side effect' of adjunctive transplant therapy

Drugs in the mTOR inhibitor class have been assessed in a meta-analysis

Ovarian cyst development is a common side effect of treatment with a class of drugs used as prophylactic immunosuppressants after organ transplants, Italian researchers say.

ovary and fallopian tube

The mTOR (mammalian target of rapamycin) inhibitor therapy class includes sirolimus, tacrolimus, everolimus and temsirolimus, which are approved for use in Australia.

The researchers searched the literature for evidence on ovarian cyst development during mTOR inhibitor treatment, finding seven eligible