Botulinum delivers 'no extra benefit' in jerky movement disorders
But this won't stop off-label use, neurologist says
18th October 2019
By Lydia Hales
Botulinum toxin appears no better than placebo for treatment of jerky and tremulous functional movement disorders, neurologists say after conducting a randomised controlled trial.
The Dutch study of 48 patients at a single clinic has found a marked placebo response, however, suggesting a substantial potential for recovery among even chronically ill patients, researchers say.
The trial participants were randomised to receive intramuscular botulinum toxin A injections or sterile saline at baseline and three months, followed by