BP hyper-reactivity to standing 'predicts cardiac events'

Younger patients with a sharp rise in systolic blood pressure on standing may need pharmacotherapy, researchers say

Orthostatic hyper-reactivity in young and middle-aged adults with stage I hypertension nearly doubles the risk of major cardiac and renal events, a multi-centre study shows.

Italian researchers say “exaggerated” systolic blood pressure (BP) responses to standing could flag the need for early pharmacotherapy and should be incorporated into future guidelines.

Based on data from 1200 participants under 45 years screened for stage I hypertension in the HARVEST