Buprenorphine-naloxone combo safe for pregnant women: study
Buprenorphine-naloxone was associated with better outcomes than buprenorphine alone on some measures.
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Buprenorphine combined with naloxone does not increase the risk of major congenital malformations in pregnant women with opioid use disorder, a Journal of the American Medical Association study has found.Â
While buprenorphine-naloxone is commonly used for opioid use disorder, the lack of perinatal safety data has limited use in pregnant women, Harvard Medical School researchers said.