Can aggressive hydration post-ERCP be abandoned?

The prophylactic approach used to prevent pancreatitis showed no significant benefit in a randomised controlled trial

Adding aggressive periprocedural hydration to rectal NSAIDs has no added benefit for protecting against pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP), a study shows.

Chinese woman in hospital on a drip

The dual therapy also did not reduce the severity of post-ERCP pancreatitis in the FLUYT randomised controlled trial compared with rectal NSAIDs alone, the Dutch investigators report.

Despite use of prophylactic rectal NSAIDs, the prevalence of post-ERCP pancreatitis remains substantial.

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