Certain IBD biologics tied to poor immune response to COVID-19 vaccine

Patients on infliximab or tofacitinib for inflammatory bowel disease have weaker immune responses to COVID-19 vaccines and should be prioritized for booster shots, UK clinicians warn.
The magnitude of reduction in antibody response following a primary course of vaccination was particularly striking in those treated with the anti-TNF therapy, results from their prospective case-control study suggest.