Child and adult asthma linked to different genes

Eventually personalised medicine approaches may mean the two patient groups are treated differently, say researchers

Child- and adult-onset asthma have some faulty genes in common, but there are also important differences, meaning optimal treatment could differ between the two, US researchers say.

DNA molecule

The study of more than 356,000 Caucasian individuals shows that while 37 genetic variants were common to both child- and adult-onset disease, 23 were unique in child-onset disease and one to adult-onset.

Clinical differences between early- and late-onset asthma were well known: adult-onset disease was more common in women, had a worse prognosis, a poorer response to corticosteroids and was less

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