Childhood IBD tied to higher cancer risk later
Crohn's disease is more strongly linked than ulcerative colitis, results suggest
Children with inflammatory bowel disease (IBD), and in particular Crohn’s disease, are at twice the risk of developing cancer in adulthood, a study shows.
Canadian researchers identified 947 patients with IBD developed before the age of 18 years (median 14 years at diagnosis) using the University of Manitoba IBD Epidemiology Database. Of these, 576 had Crohn’s disease and the remaining 371 had ulcerative colitis (UC).
Cancers diagnosed in cases and in 9272 controls between 1984 and 2018 were determined through linkage to a cancer registry.
Overall, cancer rates in the IBD patients were 114 per 100,000 person years, compared with 57 per 100,000 person years in controls — a doubling of risk.
