Cochrane backs antiplatelets to prevent pre-eclampsia

Administration to 1000 women saves 20 pregnancies from serious adverse events

Antiplatelet agents, such as aspirin and dipyridamole, are safe and effective for preventing pre-eclampsia and its complications, according to a Cochrane review.

Aspirin tablets

Dr Lelia Duley of Nottingham Health Science Partners, in the UK, and colleagues assessed the effectiveness and safety of antiplatelet drugs for preventing pre-eclampsia and its complications in their systematic review of 77 randomised trials, including more than 40,000 women and their babies.

Low-dose aspirin (75mg per day or less) was the sole intervention in all of the large trials and in

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