COVID-19 more severe with certain rheumatic diseases: study

Patients on biologics, but not conventional DMARDs, are also at increased risk, researchers say
Reuters Health Staff writer

Certain rheumatoid conditions and therapies are associated with higher risk for COVID-19, researchers say.

A study from Spain shows patients with spondyloarthritis, polymyalgia rheumatica or giant cell arteritis, and those on biologics and targeted-synthetic therapies, are at higher risk for hospital-diagnosed COVID-19 infection compared with the general population.

Data from more than 26,000 patients being treated at seven hospital rheumatology departments were checked for positive SARS-CoV-2 PCR tests and compared with a reference population of 2.9 million adults in the catchment area of the hospitals.

Overall, patients with any rheumatic disease had 1.32-fold greater odds of hospital-diagnosed COVID-19 than the reference population (0.76% vs 0.58%), the researchers report in Annals of the Rheumatic Diseases.