Is diastolic BP a modifiable risk factor for hypertrophic cardiomyopathy?
The condition is often polygenic with many common gene variants contributing risk, researchers find
Diastolic blood pressure may be a key modifiable risk factor in patients with hypertrophic cardiomyopathy who don’t carry one of the rare genetic mutations known to cause the condition, UK researchers say.
The genome-wide association study, reported in Nature Genetics, included 2780 cases of which 64% were sarcomere-negative and nearly 47,500 controls.
