Discovery offers hope for new schizophrenia drugs

Australian researchers have found that a subgroup of patients have raised kynurenic acid in the brain

A discovery that a subgroup of patients with schizophrenia have increased production of kynurenic acid in the brain could pave the way for new drug treatment targets, Australian researchers say.

Helen Cai and Professor Cyndi Shannon Weickert

During inflammation, the amino acid tryptophan is broken down into kynurenine, which either forms quinolinic or kynurenic acid.

It has previously been debated which of these leads to brain

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