Do PPIs help lower blood glucose in type 2 diabetes?
There appears to be a small reduction in HbA1c, but longer-term studies are needed, commentators say
Proton-pump inhibitors (PPIs) used to treat gastro-oesophageal reflux disease also appear to lower HbA1c levels in patients with type 2 diabetes, a study shows.
This needs to be taken into account when prescribing antacids to patients with diabetes, the investigators say.
The US researchers reviewed studies that compared HbA1c or fasting blood glucose in patients with diabetes who were treated with and without PPI therapy as add-on to standard therapy.
They analysed data from seven studies involving 342 participants to look at glycaemic control.
