Dose-intensive chemo cuts breast cancer deaths
Meta-analysis finds two ways of raising the dose are both better than standard care
12th April 2019
By Clare Pain
Giving adjuvant chemotherapy more frequently or giving drugs sequentially, rather than together, in early breast cancer reduces recurrence and mortality rates, a meta-analysis suggests.
The findings come from a study that aimed to determine whether increasing dose intensity improved patient outcomes.
The researchers, from the Early Breast Cancer Trialists’ Collaborative Group, examined data on 37,000 women, who were mostly younger than 70 with node positive disease, from 26 randomised controlled trials involving dose